SCHEMBL16194713

SCHEMBL16194713

NCC(CC(F)F)NC(=O)O

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ DNM1 Q05193 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15152152 0.81 — —
SCHEMBL26656005 0.80 SLC1A1 (0.31) —
SCHEMBL26656011 0.80 SLC1A1 (0.31) —
SCHEMBL9735086 0.78 CACNA2D1 (0.45) DNM1
SCHEMBL18341229 0.75 — —
SCHEMBL20186670 0.75 — —
SCHEMBL16094266 0.73 — —
Hydrochloric Acid SCHEMBL4887630 0.73 GLRA1 (0.35) DNM1
Hydrochloric Acid SCHEMBL18342466 0.73 GLRA1 (0.35) DNM1
Hydrochloric Acid SCHEMBL20186402 0.71 DNM1 (0.40) DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140323418-A1 SELECTIVE KINASE INHIBITORS PORTOLA PHARMACEUTICALS, INC. (US) 2014-10-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140323418-A1 SELECTIVE KINASE INHIBITORS SYK, BTK, LCK DNM1 1653/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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