Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | HRH2 | P25021 | 14/20 | 0.46 |
| ▸ | HRH1 | P35367 | 14/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1619383 | 0.96 | KCNH2 (0.51) | KCNH2HRH2HRH1HRH3MEN1 | |
| SCHEMBL4140843 | 0.87 | KCNH2 (0.51) | KCNH2HRH2HRH1HRH3MEN1 | |
| SCHEMBL4139628 | 0.84 | KCNH2 (0.48) | KCNH2HRH2HRH1HRH3MEN1 | |
| SCHEMBL2954568 | 0.84 | KCNH2 (0.52) | KCNH2HRH2HRH1HRH3MEN1 | |
| SCHEMBL4134252 | 0.83 | KCNH2 (0.53) | KCNH2HRH2HRH1HRH3MEN1 | |
| SCHEMBL1619268 | 0.83 | KCNH2 (0.51) | KCNH2HRH2HRH1HRH3MEN1 | |
| SCHEMBL2964384 | 0.82 | KCNH2 (0.56) | KCNH2HRH2HRH1HRH3MEN1 | |
| SCHEMBL3129914 | 0.82 | KCNH2 (0.54) | KCNH2HRH2HRH1HRH3MEN1 | |
| SCHEMBL2964375 | 0.80 | KCNH2 (0.54) | KCNH2HRH2HRH1HRH3MEN1 | |
| SCHEMBL1618052 | 0.80 | KCNH2 (0.48) | KCNH2HRH2HRH1HRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7928225-B2 | Oxabispidine compounds for the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2011-04-19 | — | — | US | claimed |