Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | HRH2 | P25021 | 11/20 | 0.44 |
| ▸ | HRH1 | P35367 | 11/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1619268 | 0.97 | KCNH2 (0.51) | KCNH2HRH2HRH1HRH3MEN1 | |
| SCHEMBL1619682 | 0.91 | KCNH2 (0.45) | KCNH2HRH2HRH1HRH3MEN1 | |
| SCHEMBL1619296 | 0.87 | KCNH2 (0.60) | KCNH2HRH2HRH1HRH3MEN1 | |
| SCHEMBL1619299 | 0.87 | KCNH2 (0.60) | KCNH2HRH2HRH1HRH3MEN1 | |
| SCHEMBL4139628 | 0.87 | KCNH2 (0.48) | KCNH2HRH2HRH1HRH3MEN1 | |
| SCHEMBL1619395 | 0.87 | HRH3 (0.45) | KCNH2HRH3KDM4EHTT | |
| SCHEMBL1619584 | 0.84 | KCNH2 (0.41) | KCNH2HRH2HRH1HRH3MEN1 | |
| SCHEMBL4507239 | 0.84 | KCNH2 (0.43) | KCNH2HRH2HRH1HRH3MEN1 | |
| SCHEMBL5013138 | 0.84 | MMP2 (0.41) | KCNH2HRH2HRH1HRH3MEN1 | |
| SCHEMBL4140843 | 0.84 | KCNH2 (0.51) | KCNH2HRH2HRH1HRH3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7928225-B2 | Oxabispidine compounds for the treatment of cardiac arrhythmias | ASTRAZENECA AB (SE) | 2011-04-19 | — | — | US | disclosed |