SCHEMBL16196171

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16206993	0.94	EGFR (0.72)	EGFRCTSCPLK4GAKNUAK1
	SCHEMBL16207003	0.89	EGFR (0.89)	EGFRCTSCJAK2BLKBMX
	SCHEMBL16195522	0.89	EGFR (1.00)	EGFRCTSCNUAK1JAK2BLK
	SCHEMBL16207309	0.87	EGFR (0.90)	EGFRCTSCPLK4GAKJAK2
	SCHEMBL16195665	0.87	EGFR (1.00)	EGFRCTSCEML4ALK
	SCHEMBL16207139	0.87	EGFR (0.94)	EGFRCTSCNUAK1JAK2BLK
	SCHEMBL16195470	0.87	EGFR (0.94)	EGFRCTSCNUAK1JAK2BLK
	SCHEMBL16207010	0.84	EGFR (0.82)	EGFRCTSCPLK4GAKNUAK1
	SCHEMBL16206979	0.84	EGFR (0.87)	EGFRCTSCJAK2FLT3JAK3
	SCHEMBL16207128	0.84	EGFR (0.84)	EGFRFLT3EML4ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.