Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 17/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 1/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | HPGD | P15428 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 0.83 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fentiazac SCHEMBL24355 | 1.00 | PTGDR2 (1.00) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL1514667 | 1.00 | PTGDR2 (1.00) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| Fentiazac SCHEMBL5390943 | 0.99 | PTGDR2 (0.97) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL4497493 | 0.91 | PTGDR2 (1.00) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL11100736 | 0.90 | PTGDR2 (0.82) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL13116312 | 0.89 | PTGDR2 (0.81) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL12608906 | 0.89 | PTGDR2 (0.81) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL5210404 | 0.86 | PTGDR2 (0.76) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL2818129 | 0.86 | PTGDR2 (1.00) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL13116322 | 0.85 | PTGDR2 (0.74) | PTGDR2KDM4EALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014172776-A1 | COMPOUNDS FOR THE TREATMENT OF MUCOPOLYSACCHARIDOSES | THE HOSPITAL FOR SICK CHILDREN (CA) | 2014-10-30 | — | — | WO | disclosed |