Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | AHR | P35869 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16196756 | 0.84 | KDM4E (0.41) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL16196757 | 0.84 | KDM4E (0.41) | ALDH1A1HSD17B10TDP1 | |
| SCHEMBL16196790 | 0.83 | AKR1C3 (0.33) | — | |
| SCHEMBL16196791 | 0.83 | AKR1C3 (0.33) | — | |
| SCHEMBL16197181 | 0.83 | PPARA (0.33) | — | |
| SCHEMBL16205422 | 0.81 | — | — | |
| SCHEMBL16205423 | 0.81 | — | — | |
| SCHEMBL16013778 | 0.81 | — | — | |
| SCHEMBL16013858 | 0.81 | MAPT (0.31) | ALDH1A1TDP1 | |
| SCHEMBL16013802 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014172871-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-30 | — | — | WO | disclosed |
| WO-2014172871-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-30 | — | — | WO | disclosed |