⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16013858 | 0.84 | MAPT (0.31) | — | |
| SCHEMBL16013778 | 0.84 | — | — | |
| SCHEMBL16196868 | 0.82 | PPARA (0.32) | — | |
| SCHEMBL16196813 | 0.82 | PNMT (0.33) | — | |
| SCHEMBL16196771 | 0.81 | ALDH1A1 (0.34) | — | |
| SCHEMBL16196770 | 0.81 | PPARA (0.34) | — | |
| SCHEMBL16197179 | 0.79 | NPC1 (0.35) | — | |
| SCHEMBL16197181 | 0.79 | PPARA (0.33) | — | |
| SCHEMBL16196832 | 0.79 | ACHE (0.32) | — | |
| SCHEMBL16013937 | 0.79 | PNMT (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9598389-B2 | Dihydrobenzofuran derivatives as insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-21 | — | — | US | disclosed |
| US-9598389-B2 | Dihydrobenzofuran derivatives as insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-21 | — | — | US | disclosed |
| US-9598389-B2 | Dihydrobenzofuran derivatives as insecticidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2017-03-21 | — | — | US | disclosed |
| US-20160016927-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-21 | — | — | US | disclosed |
| US-20160016927-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-21 | — | — | US | disclosed |
| US-20160016927-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-21 | — | — | US | disclosed |
| EP-2964025-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2016-01-13 | — | — | EP | disclosed |
| WO-2014135095-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-09-12 | — | — | WO | disclosed |
| WO-2014135095-A1 | DIHYDROBENZOFURAN DERIVATIVES AS INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-09-12 | — | — | WO | disclosed |