Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PORCN | Q9H237 | 7/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | WNT3A | P56704 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16201300 | 0.86 | PORCN (0.71) | PORCNCYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL16201307 | 0.86 | PORCN (0.80) | PORCNCYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL16201462 | 0.85 | PORCN (0.79) | PORCNCYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL16197934 | 0.83 | PORCN (1.00) | PORCNCYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL16201303 | 0.81 | PORCN (0.78) | PORCNCYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL16197998 | 0.81 | PORCN (0.75) | PORCNCYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL16198018 | 0.80 | CYP3A4 (0.68) | PORCNCYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL16201507 | 0.80 | PORCN (0.68) | PORCNCYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL16198083 | 0.80 | PORCN (0.74) | PORCNCYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL16198312 | 0.80 | PORCN (0.84) | PORCNCYP3A4CYP2D6LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014175832-A1 | WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-10-30 | — | — | WO | disclosed |
| WO-2014175832-A1 | WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-10-30 | — | — | WO | disclosed |