Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4367585 | 1.00 | HSD11B1 (0.77) | HSD11B1CYP3A4 | |
| SCHEMBL4367555 | 0.87 | HSD11B1 (1.00) | HSD11B1CYP3A4 | |
| SCHEMBL4632177 | 0.87 | HSD11B1 (1.00) | HSD11B1CYP3A4 | |
| SCHEMBL15151493 | 0.87 | HSD11B1 (1.00) | HSD11B1CYP3A4 | |
| SCHEMBL4371742 | 0.87 | HSD11B1 (1.00) | HSD11B1CYP3A4 | |
| SCHEMBL4367372 | 0.87 | HSD11B1 (0.65) | HSD11B1CYP3A4 | |
| SCHEMBL4367485 | 0.85 | HSD11B1 (0.71) | HSD11B1CYP3A4 | |
| SCHEMBL4367478 | 0.85 | HSD11B1 (1.00) | HSD11B1CYP3A4 | |
| SCHEMBL4666480 | 0.85 | HSD11B1 (1.00) | HSD11B1CYP3A4 | |
| SCHEMBL4367500 | 0.84 | HSD11B1 (0.67) | HSD11B1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871208-B2 | 11-β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitors and uses thereof | ABBVIE INC. (US) | 2014-10-28 | — | — | US | disclosed |