Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.42 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1737049 | 1.00 | PNP (0.48) | PNPLMNATHRBMTORMDM2 | |
| SCHEMBL12300437 | 1.00 | PNP (0.48) | PNPLMNATHRBMTORMDM2 | |
| SCHEMBL6726990 | 1.00 | PNP (0.48) | PNPLMNATHRBMTORMDM2 | |
| SCHEMBL12154680 | 1.00 | PNP (0.48) | PNPLMNATHRBMTORMDM2 | |
| SCHEMBL12150649 | 1.00 | PNP (0.48) | PNPLMNATHRBMTORMDM2 | |
| SCHEMBL1736631 | 0.88 | LMNA (0.40) | PNPLMNATHRBMTORMDM2 | |
| SCHEMBL12030542 | 0.88 | LMNA (0.40) | PNPLMNATHRBMTORMDM2 | |
| SCHEMBL12154737 | 0.87 | PNP (0.59) | PNPLMNATHRBMTORMDM2 | |
| SCHEMBL19049975 | 0.87 | PNP (0.59) | PNPLMNATHRBMTORMDM2 | |
| SCHEMBL1738311 | 0.87 | PNP (0.59) | PNPLMNATHRBMTORMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871785-B2 | Antiviral phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2014-10-28 | — | — | US | disclosed |