Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDA | P32320 | 4/20 | 0.40 |
| ▸ | TOP1 | P11387 | 2/20 | 0.35 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.34 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MTOR | P42345 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16199346 | 1.00 | CDA (0.40) | CDATOP1SLC28A1SLC28A2SLC29A1 | |
| SCHEMBL10024098 | 0.90 | CDA (0.48) | CDASLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL6424353 | 0.88 | CDA (0.45) | CDASLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL16409714 | 0.80 | CDA (0.32) | CDA | |
| SCHEMBL16198960 | 0.77 | — | — | |
| SCHEMBL20356797 | 0.76 | CDA (0.50) | CDASLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL14178409 | 0.76 | ADK (0.39) | — | |
| SCHEMBL14199831 | 0.76 | ADK (0.39) | — | |
| SCHEMBL15070549 | 0.74 | CDA (0.49) | CDASLC29A1LMNASMN1; SMN2 | |
| SCHEMBL16643735 | 0.74 | CDA (0.49) | CDASLC29A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871785-B2 | Antiviral phosphonate analogs | GILEAD SCIENCES, INC. (US) | 2014-10-28 | — | — | US | disclosed |