Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.37 |
| ▸ | RAF1 | P04049 | 4/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | F9 | P00740 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1725936 | 0.93 | CYP4F2 (0.42) | CYP4F2CYP4A11ABL1MAPTMETTL3 | |
| SCHEMBL3106620 | 0.80 | TSHR (0.41) | CYP4F2CYP4A11MAPTTDP1DGAT1 | |
| SCHEMBL3100899 | 0.79 | PTGES (0.43) | CYP4F2CYP4A11 | |
| SCHEMBL1671454 | 0.70 | CYP4F2 (0.73) | CYP4F2CYP4A11METTL3CA12CA1 | |
| SCHEMBL1971881 | 0.68 | HDAC11 (0.41) | MAPTHDAC11HPGD | |
| SCHEMBL1975779 | 0.68 | MAPT (0.41) | ABL1MAPT | |
| SCHEMBL1967114 | 0.68 | HDAC11 (0.42) | ABL1MAPTMETTL3HDAC11TDP1 | |
| SCHEMBL1966839 | 0.68 | PTGES (0.40) | ABL1MAPTMETTL3HDAC11 | |
| SCHEMBL1725058 | 0.67 | PTGES (0.40) | MAPTSIRT2SIRT1SIRT3 | |
| SCHEMBL1964833 | 0.66 | PTGES (0.41) | ABL1HDAC11DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403852-B1 | 2-AMINOBENZIMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INT (DE) | 2014-10-29 | — | — | EP | disclosed |