Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.33 |
| ▸ | TCF7L2 | Q9NQB0 | 3/20 | 0.33 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13189710 | 0.79 | CTNNB1 (0.41) | NR2E3MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL13190105 | 0.79 | PTGES (0.40) | NR2E3MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL11962208 | 0.79 | PTGES (0.41) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL13190114 | 0.78 | PTGES (0.39) | NR2E3MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL13190111 | 0.78 | PTGES (0.42) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL13190116 | 0.77 | MAPT (0.39) | NR2E3MAPTKMT2AMEN1ALDH1A1 | |
| SCHEMBL13189730 | 0.77 | PTGES (0.38) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL13189727 | 0.77 | MAPT (0.42) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL13189698 | 0.76 | MAPT (0.41) | MAPTKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL16199767 | 0.74 | LPAR2 (0.44) | MAPTKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403852-B1 | 2-AMINOBENZIMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INT (DE) | 2014-10-29 | — | — | EP | disclosed |