Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 20/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3099096 | 0.85 | PTGES (0.58) | PTGES | |
| SCHEMBL1725041 | 0.77 | PTGES (0.80) | PTGES | |
| SCHEMBL3106287 | 0.76 | PTGES (0.47) | PTGES | |
| SCHEMBL16199745 | 0.75 | PTGES (0.49) | PTGES | |
| SCHEMBL3101702 | 0.73 | PTGES (0.73) | PTGES | |
| SCHEMBL3093201 | 0.73 | PTGES (0.69) | PTGES | |
| SCHEMBL3100417 | 0.72 | PTGES (0.68) | PTGES | |
| SCHEMBL16192711 | 0.72 | PTGES (0.62) | PTGES | |
| SCHEMBL3109419 | 0.71 | PTGES (0.66) | PTGES | |
| SCHEMBL3099526 | 0.71 | PTGES (0.58) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403852-B1 | 2-AMINOBENZIMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INT (DE) | 2014-10-29 | — | — | EP | disclosed |