Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 20/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3109637 | 0.86 | PTGES (0.67) | PTGES | |
| SCHEMBL3109624 | 0.86 | PTGES (0.67) | PTGES | |
| SCHEMBL670920 | 0.79 | PTGES (0.73) | PTGES | |
| SCHEMBL13190115 | 0.79 | RAF1 (0.36) | PTGES | |
| SCHEMBL16199747 | 0.79 | RAF1 (0.37) | — | |
| SCHEMBL16199768 | 0.78 | RAF1 (0.37) | — | |
| SCHEMBL11961902 | 0.72 | PTGES (0.63) | PTGES | |
| SCHEMBL11985102 | 0.72 | PTGES (0.49) | PTGES | |
| SCHEMBL670785 | 0.72 | PTGES (0.76) | PTGES | |
| SCHEMBL11962197 | 0.72 | PTGES (0.49) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403852-B1 | 2-AMINOBENZIMIDAZOLE-5-CARBOXAMIDES AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INT (DE) | 2014-10-29 | — | — | EP | disclosed |