Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | PIK3R2 | O00459 | 4/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | SLC34A1 | Q06495 | 3/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16200174 | 0.81 | DYRK1A (0.41) | SLC34A1 | |
| SCHEMBL13184409 | 0.72 | MYC (0.39) | MYCNPY5RXDHABCG2PIK3R2 | |
| SCHEMBL9792895 | 0.71 | MYC (0.62) | MYCNPY5RXDHABCG2LRRK2 | |
| SCHEMBL31133396 | 0.71 | MYC (0.62) | MYCNPY5RXDHABCG2LRRK2 | |
| SCHEMBL16200290 | 0.70 | XDH (0.46) | MYCNPY5RXDHABCG2PIK3R2 | |
| SCHEMBL29239106 | 0.70 | MYC (0.44) | MYCNPY5RXDHABCG2PIK3R2 | |
| SCHEMBL15731252 | 0.69 | MYC (0.43) | MYCNPY5RXDHABCG2LRRK2 | |
| SCHEMBL14411171 | 0.69 | CSNK1D (0.64) | NPY5R | |
| SCHEMBL2952766 | 0.67 | MYC (0.59) | MYCNPY5RXDHABCG2CYP3A4 | |
| SCHEMBL12439756 | 0.67 | MYC (0.41) | MYCNPY5RXDHABCG2PIK3R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720545-B1 | BICYCLIC AND BRIDGED NITROGEN HETEROCYCLES | CHEMOCENTRYX INC (US) | 2014-10-29 | — | — | EP | disclosed |