SCHEMBL16201008

SCHEMBL16201008

COc1ccc2c3c(cccc13)-c1ccccc1-2

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRMT1 Q99873 1/20 0.64
MAPT P10636 9/20 0.62
KMT2A Q03164 8/20 0.62
KDM4E B2RXH2 5/20 0.62
ALDH1A1 P00352 5/20 0.62
POLB P06746 2/20 0.62
PABPC1 P11940 2/20 0.62
LMNA P02545 1/20 0.62
XBP1 P17861 1/20 0.62
NFKB1 P19838 1/20 0.62
HTT P42858 1/20 0.62
SMARCA2 P51531 1/20 0.62
NFKB2 Q00653 1/20 0.62
RELA Q04206 1/20 0.62
MEN1 O00255 6/20 0.54
USP2 O75604 4/20 0.51
S100A4 P26447 1/20 0.51
CASP1 P29466 3/20 0.50
HSD17B10 Q99714 3/20 0.50
CASP7 P55210 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3380389 0.89 MAPT (0.63) PRMT1MAPTKMT2AKDM4EALDH1A1
SCHEMBL12019937 0.85 IDO1 (0.59) PRMT1MAPTKMT2AKDM4EALDH1A1
SCHEMBL12019868 0.85 IDO1 (0.59) PRMT1MAPTKMT2AKDM4EALDH1A1
SCHEMBL14241626 0.84 PRMT1 (0.47) PRMT1MAPTKMT2AKDM4EALDH1A1
SCHEMBL12941557 0.84 PRMT1 (0.70) PRMT1MAPTKMT2AKDM4EALDH1A1
SCHEMBL11592771 0.83 KMT2A (0.65) PRMT1MAPTKMT2AKDM4EALDH1A1
SCHEMBL13878093 0.82 MAPT (0.51) PRMT1MAPTKMT2AKDM4EALDH1A1
SCHEMBL12726429 0.81 PRMT1 (0.45) PRMT1MAPTKMT2AKDM4EALDH1A1
SCHEMBL6548245 0.81 KMT2A (0.76) PRMT1MAPTKMT2AKDM4EALDH1A1
SCHEMBL30761754 0.81 KMT2A (0.76) PRMT1MAPTKMT2AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9298115-B2 Electrophotographic photosensitive member, method for manufacturing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2016-03-29 US disclosed
US-20140322637-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR MANUFACTURING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2014-10-30 US disclosed