Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PORCN | Q9H237 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ADH5 | P11766 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16198072 | 0.90 | PORCN (0.70) | PORCNCYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL16201472 | 0.85 | PORCN (0.77) | PORCNCYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL16198251 | 0.83 | PORCN (0.71) | PORCNCYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL16197880 | 0.81 | PORCN (0.74) | PORCNCYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL16198252 | 0.78 | PORCN (0.66) | PORCNCYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL16198074 | 0.76 | PORCN (0.72) | PORCNCYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL16197898 | 0.74 | PORCN (0.82) | PORCNCYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL16198249 | 0.73 | PORCN (0.80) | PORCNCYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL16197934 | 0.72 | PORCN (1.00) | PORCNCYP3A4CYP2D6LMNAMAPT | |
| SCHEMBL16201464 | 0.72 | PORCN (0.68) | PORCNCYP3A4CYP2D6LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014175832-A1 | WNT PATHWAY MODULATORS | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2014-10-30 | — | — | WO | disclosed |