SCHEMBL16201731

SCHEMBL16201731

Cc1ccc(N(c2ccc3c(c2)C(C)(C)c2cc(N(c4ccc(C)cc4)c4ccc5ccccc5c4)c4ccccc4c2-3)c2ccc3ccccc3c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP2A6 P11509 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16201703 0.93 KDM4E (0.30)
SCHEMBL17524531 0.93
SCHEMBL16201761 0.92 CYP2A6 (0.32) CYP2A6TDP1
SCHEMBL16201749 0.92 HTT (0.31) HTTNPSR1L3MBTL1
SCHEMBL16144137 0.91 CYP2A6 (0.31) CYP2A6TDP1
SCHEMBL16201747 0.91 TDP1 (0.34) HTTNPSR1L3MBTL1CYP2A6TDP1
SCHEMBL21515585 0.91 APP (0.30)
SCHEMBL26485374 0.91 APP (0.30)
SCHEMBL16144140 0.90 CYP1A2 (0.32) CYP2A6
SCHEMBL16201762 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9590182-B2 Benzofluorene compound, material for luminescent layer using said compound and organic electroluminescent device JNC CORPORATION (JP) 2017-03-07 US disclosed
US-9590182-B2 Benzofluorene compound, material for luminescent layer using said compound and organic electroluminescent device JNC CORPORATION (JP) 2017-03-07 US disclosed
US-20140319510-A1 BENZOFLUORENE COMPOUND, MATERIAL FOR LUMINESCENT LAYER USING SAID COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE JNC CORPORATION (JP) 2014-10-30 US disclosed
US-20140319510-A1 BENZOFLUORENE COMPOUND, MATERIAL FOR LUMINESCENT LAYER USING SAID COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE JNC CORPORATION (JP) 2014-10-30 US disclosed