SCHEMBL16144140

SCHEMBL16144140

CC1(C)c2cc(N(c3ccc(F)cc3)c3ccc4ccccc4c3)ccc2-c2c1cc(N(c1ccc(F)cc1)c1ccc3ccccc3c1)c1ccccc21

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.32
CYP2A6 P11509 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16219659 0.94 PDK2 (0.33)
SCHEMBL16201703 0.92 KDM4E (0.30)
SCHEMBL16144141 0.91 ABCG2 (0.31) CYP1A2CYP2A6
SCHEMBL16219676 0.91 PDK2 (0.36)
SCHEMBL24236337 0.91 PDK2 (0.31)
SCHEMBL16219606 0.90 GPR84 (0.32) CYP1A2CYP2A6
SCHEMBL16201760 0.90
SCHEMBL16201731 0.90 HTT (0.36) CYP2A6
SCHEMBL16219633 0.90 PDK2 (0.35)
SCHEMBL16201740 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9590182-B2 Benzofluorene compound, material for luminescent layer using said compound and organic electroluminescent device JNC CORPORATION (JP) 2017-03-07 US disclosed
US-9590182-B2 Benzofluorene compound, material for luminescent layer using said compound and organic electroluminescent device JNC CORPORATION (JP) 2017-03-07 US disclosed
US-20140319510-A1 BENZOFLUORENE COMPOUND, MATERIAL FOR LUMINESCENT LAYER USING SAID COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE JNC CORPORATION (JP) 2014-10-30 US disclosed
US-20140319510-A1 BENZOFLUORENE COMPOUND, MATERIAL FOR LUMINESCENT LAYER USING SAID COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE JNC CORPORATION (JP) 2014-10-30 US disclosed
EP-2784057-A1 BENZOFLUORENE COMPOUND, MATERIAL FOR LUMINESCENT LAYER USING SAID COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE JNC Corporation (JP) 2014-10-01 EP disclosed