Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CTSC | P53634 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.42 |
| ▸ | ANPEP | P15144 | 2/20 | 0.42 |
| ▸ | IL1RN | P18510 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16201774 | 1.00 | TSHR (0.44) | TSHRCTSCKMT2AERAP1ERAP2 | |
| SCHEMBL16194341 | 0.88 | ERAP1 (0.46) | TSHRKMT2AERAP1ERAP2ANPEP | |
| SCHEMBL16194340 | 0.88 | ERAP1 (0.46) | TSHRKMT2AERAP1ERAP2ANPEP | |
| SCHEMBL16201815 | 0.88 | ERAP1 (0.46) | TSHRKMT2AERAP1ERAP2ANPEP | |
| SCHEMBL16194598 | 0.84 | CSNK1E (0.52) | KMT2AHPGDTRPA1CNR2 | |
| SCHEMBL16194597 | 0.84 | CSNK1E (0.52) | KMT2AHPGDTRPA1CNR2 | |
| SCHEMBL16201776 | 0.80 | CYP2C19 (0.41) | TSHRKMT2AERAP1ERAP2ANPEP | |
| SCHEMBL16201773 | 0.80 | CYP2C19 (0.41) | TSHRKMT2AERAP1ERAP2ANPEP | |
| SCHEMBL7483571 | 0.78 | ERAP1 (0.51) | TSHRCTSCKMT2AERAP1ERAP2 | |
| SCHEMBL16201777 | 0.78 | CNR2 (0.46) | TSHRKMT2AERAP1ERAP2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140323457-A1 | BETA-O/S/N FATTY ACID BASED COMPOUNDS AS ANTIBACTERIAL AND ANTIPROTOZOAL AGENTS | Technische Universität München (DE) | 2014-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323457-A1 | BETA-O/S/N FATTY ACID BASED COMPOUNDS AS ANTIBACTERIAL AND ANTIPROTOZOAL AGENTS | FASN, DEGS1, EBP | TSHR 4582/4885CTSC 2172/4885KMT2A 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.