SCHEMBL16194597

SCHEMBL16194597

CCCCCCCCCC(C(N)=O)C(O)CCc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 1/20 0.52
S1PR2 O95136 2/20 0.47
S1PR1 P21453 2/20 0.47
MMP3 P08254 1/20 0.47
S1PR3 Q99500 1/20 0.46
CNR2 P34972 1/20 0.45
CETP P11597 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
PTGES O14684 1/20 0.43
ALOX5 P09917 1/20 0.43
PPARG P37231 1/20 0.43
HPGD P15428 1/20 0.43
SIGMAR1 Q99720 2/20 0.42
TRPA1 O75762 1/20 0.42
FAAH O00519 1/20 0.41
CYSLTR2 Q9NS75 1/20 0.41
CYSLTR1 Q9Y271 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16194598 1.00 CSNK1E (0.52) CSNK1ES1PR2S1PR1MMP3S1PR3
SCHEMBL15013828 0.90 S1PR2 (0.44) CSNK1ES1PR2S1PR1MMP3S1PR3
SCHEMBL16194341 0.85 ERAP1 (0.46) CNR2TRPA1KMT2A
SCHEMBL16194340 0.85 ERAP1 (0.46) CNR2TRPA1KMT2A
SCHEMBL16201815 0.85 ERAP1 (0.46) CNR2TRPA1KMT2A
SCHEMBL16201818 0.84 TSHR (0.44) CNR2HPGDTRPA1KMT2A
SCHEMBL16201774 0.84 TSHR (0.44) CNR2HPGDTRPA1KMT2A
SCHEMBL16201794 0.83 FAAH (0.39) S1PR2S1PR1S1PR3TRPA1FAAH
SCHEMBL15005076 0.83 FAAH (0.39) S1PR2S1PR1S1PR3TRPA1FAAH
SCHEMBL12054898 0.82 CSNK1E (0.64) CSNK1ES1PR2S1PR1S1PR3CNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2898880-A1 Beta-O/S/N fatty acid based compounds as antibacterial and antiprotozoal agents Ludwig-Maximilians-Universität München (DE) 2015-07-29 EP disclosed
US-20140323457-A1 BETA-O/S/N FATTY ACID BASED COMPOUNDS AS ANTIBACTERIAL AND ANTIPROTOZOAL AGENTS Technische Universität München (DE) 2014-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140323457-A1 BETA-O/S/N FATTY ACID BASED COMPOUNDS AS ANTIBACTERIAL AND ANTIPROTOZOAL AGENTS FASN, DEGS1, EBP CSNK1E 3199/4885S1PR2 1096/4885S1PR1 1009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.