Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10137023 | 0.85 | POLB (0.54) | KMT2AMAPTGAAKDM4ETDP1 | |
| SCHEMBL13846427 | 0.84 | MAPT (0.56) | KMT2AMAPTGAAKDM4ETDP1 | |
| SCHEMBL13846441 | 0.84 | TDP1 (0.59) | KMT2AMAPTGAAKDM4ETDP1 | |
| SCHEMBL4938228 | 0.80 | KMT2A (0.62) | KMT2AMAPTMEN1TP53POLB | |
| SCHEMBL29651063 | 0.80 | KMT2A (0.62) | KMT2AMAPTMEN1TP53POLB | |
| SCHEMBL17885425 | 0.79 | MAPT (0.69) | KMT2AMAPTGAAKDM4ETDP1 | |
| SCHEMBL6857302 | 0.77 | KMT2A (0.65) | KMT2AMAPTGAAMEN1TP53 | |
| SCHEMBL15706718 | 0.77 | MAPT (0.50) | KMT2AMAPTGAAKDM4ETDP1 | |
| SCHEMBL17625618 | 0.76 | KMT2A (0.41) | KMT2AMAPTGAAKDM4ETDP1 | |
| SCHEMBL11569245 | 0.76 | SMN1; SMN2 (0.43) | KMT2AMAPTGAAKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160087295-A1 | Catalyst and Process for the Production of Hydrogen from Ammonia Boranes | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2016-03-24 | — | — | US | disclosed |
| US-20160087295-A1 | Catalyst and Process for the Production of Hydrogen from Ammonia Boranes | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN (IE) | 2016-03-24 | — | — | US | disclosed |
| WO-2014174465-A2 | PROCESS | NOVAUCD (IE) | 2014-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160087295-A1 | Catalyst and Process for the Production of Hydrogen from Ammonia Boranes | HRH4, NR1H3, NR1H2 | KMT2A 2731/4885MAPT 4863/4885GAA 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.