Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.58 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.58 |
| ▸ | DTYMK | P23919 | 4/20 | 0.57 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.55 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.55 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.55 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.52 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.52 |
| ▸ | SRC | P12931 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.52 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16690937 | 0.91 | POLB (0.60) | POLBP2RY1ENPP1DTYMKP2RX3 | |
| SCHEMBL1763078 | 0.90 | POLB (0.65) | POLBP2RY1ENPP1DTYMKP2RX3 | |
| SCHEMBL245486 | 0.90 | POLB (0.65) | POLBP2RY1ENPP1DTYMKP2RX3 | |
| SCHEMBL29465233 | 0.90 | POLB (0.65) | POLBP2RY1ENPP1DTYMKP2RX3 | |
| SCHEMBL12943893 | 0.89 | POLB (0.62) | POLBP2RY1ENPP1DTYMKP2RX3 | |
| SCHEMBL5044161 | 0.89 | POLB (0.80) | POLBP2RY1ENPP1DTYMKP2RX3 | |
| SCHEMBL14471000 | 0.89 | POLB (0.80) | POLBP2RY1ENPP1DTYMKP2RX3 | |
| SCHEMBL703733 | 0.89 | POLB (0.80) | POLBP2RY1ENPP1DTYMKP2RX3 | |
| SCHEMBL17117824 | 0.89 | POLB (0.64) | POLBP2RY1ENPP1DTYMKP2RX3 | |
| SCHEMBL18785117 | 0.89 | POLB (0.80) | POLBP2RY1ENPP1DTYMKP2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140323354-A1 | Chemically Modified Ligase Cofactors, Donors and Acceptors | TRILINK BIOTECHNOLOGIES, INC. (US) | 2014-10-30 | — | — | US | disclosed |