SCHEMBL1620489

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29636410	0.83	ALDH1A1 (0.65)	ALDH1A1KDM4ETSHRTDP1PRKDC
	SCHEMBL71268	0.83	ALDH1A1 (0.65)	ALDH1A1KDM4ETSHRTDP1PRKDC
	SCHEMBL1620606	0.82	PRKDC (0.70)	ALDH1A1KDM4ETSHRTDP1PRKDC
	SCHEMBL87864	0.80	ALDH1A1 (0.52)	ALDH1A1KDM4ETSHRTDP1PRKDC
	SCHEMBL2702221	0.78	PRKDC (0.46)	ALDH1A1KDM4ETSHRTDP1PRKDC
	SCHEMBL1620349	0.78	ALDH1A1 (0.42)	ALDH1A1KDM4ETSHRTDP1PRKDC
	SCHEMBL29524066	0.77	ALDH1A1 (0.73)	ALDH1A1KDM4ETSHRTDP1PRKDC
	SCHEMBL15666012	0.77	ALDH1A1 (0.73)	ALDH1A1KDM4ETSHRTDP1PRKDC
	SCHEMBL32675743	0.77	ALDH1A1 (0.37)	ALDH1A1KDM4ETSHRTDP1PRKDC
	SCHEMBL436131	0.76	ALDH1A1 (0.54)	ALDH1A1KDM4ETSHRTDP1PRKDC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.