Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 14/20 | 0.58 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.58 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.58 |
| ▸ | DRD1 | P21728 | 2/20 | 0.58 |
| ▸ | DRD4 | P21917 | 2/20 | 0.58 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17074617 | 0.96 | ADRB2 (0.58) | ADRB2ADRB1CHRM3DRD2DRD1 | |
| SCHEMBL14166243 | 0.94 | ADRB2 (0.59) | ADRB2ADRB1CHRM3DRD2DRD1 | |
| Formic Acid SCHEMBL16205012 | 0.94 | ADRB2 (0.58) | ADRB2ADRB1CHRM3DRD2DRD1 | |
| Formic Acid SCHEMBL17074740 | 0.90 | ADRB2 (0.57) | ADRB2ADRB1CHRM3DRD2DRD1 | |
| SCHEMBL14166020 | 0.90 | ADRB2 (0.61) | ADRB2ADRB1CHRM3ADRB3 | |
| SCHEMBL17074633 | 0.90 | ADRB2 (0.61) | ADRB2ADRB1CHRM3ADRB3 | |
| SCHEMBL17074632 | 0.90 | ADRB2 (0.61) | ADRB2ADRB1CHRM3ADRB3 | |
| SCHEMBL14166259 | 0.89 | ADRB2 (0.65) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL16205038 | 0.89 | ADRB2 (0.59) | ADRB2ADRB1DRD2DRD1DRD4 | |
| SCHEMBL17074656 | 0.88 | ADRB2 (0.64) | ADRB2ADRB1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718280-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMA SPA (IT) | 2015-09-16 | — | — | EP | claimed |
| US-8877774-B2 | Compounds having muscarinic receptor antagonist and beta2 Adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-11-04 | — | — | US | claimed |
| EP-2718280-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMA SPA (IT) | 2015-09-16 | — | — | EP | disclosed |