Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 16/20 | 0.74 |
| ▸ | CHRM3 | P20309 | 13/20 | 0.74 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16205035 | 1.00 | ADRB2 (0.74) | ADRB2CHRM3ADRB1 | |
| SCHEMBL16205030 | 1.00 | ADRB2 (0.74) | ADRB2CHRM3ADRB1 | |
| SCHEMBL15777978 | 0.95 | ADRB2 (0.67) | ADRB2CHRM3ADRB1 | |
| SCHEMBL15777980 | 0.95 | ADRB2 (0.67) | ADRB2CHRM3ADRB1 | |
| SCHEMBL15777982 | 0.95 | ADRB2 (0.67) | ADRB2CHRM3ADRB1 | |
| SCHEMBL20357860 | 0.95 | ADRB2 (0.67) | ADRB2CHRM3ADRB1 | |
| SCHEMBL17082532 | 0.95 | ADRB2 (0.67) | ADRB2CHRM3ADRB1 | |
| SCHEMBL14166362 | 0.94 | ADRB2 (0.66) | ADRB2CHRM3ADRB1 | |
| SCHEMBL14166365 | 0.94 | ADRB2 (0.66) | ADRB2CHRM3ADRB1 | |
| SCHEMBL14166364 | 0.94 | ADRB2 (0.66) | ADRB2CHRM3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718280-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMA SPA (IT) | 2015-09-16 | — | — | EP | claimed |
| US-8877774-B2 | Compounds having muscarinic receptor antagonist and beta2 Adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-11-04 | — | — | US | claimed |