Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 18/20 | 0.67 |
| ▸ | CHRM3 | P20309 | 15/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.60 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16205090 | 1.00 | ADRB2 (0.67) | ADRB2CHRM3ADRB1CACNA1C | |
| SCHEMBL16205089 | 1.00 | ADRB2 (0.67) | ADRB2CHRM3ADRB1CACNA1C | |
| SCHEMBL14166089 | 0.95 | ADRB2 (0.73) | ADRB2CHRM3ADRB1 | |
| SCHEMBL16204965 | 0.95 | ADRB2 (0.73) | ADRB2CHRM3ADRB1 | |
| SCHEMBL17074696 | 0.95 | ADRB2 (0.73) | ADRB2CHRM3ADRB1 | |
| SCHEMBL14166091 | 0.95 | ADRB2 (0.73) | ADRB2CHRM3ADRB1 | |
| SCHEMBL14694679 | 0.95 | ADRB2 (0.73) | ADRB2CHRM3ADRB1 | |
| SCHEMBL14166120 | 0.95 | ADRB2 (0.73) | ADRB2CHRM3ADRB1 | |
| SCHEMBL16205167 | 0.95 | ADRB2 (0.73) | ADRB2CHRM3ADRB1 | |
| SCHEMBL17074694 | 0.95 | ADRB2 (0.73) | ADRB2CHRM3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718280-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMA SPA (IT) | 2015-09-16 | — | — | EP | claimed |
| US-8877774-B2 | Compounds having muscarinic receptor antagonist and beta2 Adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-11-04 | — | — | US | claimed |