Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 17/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 17/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 10/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3517380 | 1.00 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL3521364 | 1.00 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL1607 | 0.95 | SLC6A4 (0.90) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL2374 | 0.93 | SLC6A4 (0.88) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL16298324 | 0.86 | SLC6A4 (0.76) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL3517022 | 0.83 | SLC6A4 (0.71) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL3520295 | 0.83 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL3521011 | 0.83 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 | |
| SCHEMBL3517010 | 0.81 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2KCNH2 | |
| SCHEMBL3516278 | 0.81 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2KCNH2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877975-B2 | Cycloalkylamines as monoamine reuptake inhibitors | SUNOVION PHARMACEUTICALS INC. (US) | 2014-11-04 | — | — | US | claimed |