Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16208095 | 0.89 | HSD11B1 (0.60) | HSD11B1CYP3A4CYP2C19 | |
| SCHEMBL16208216 | 0.89 | HSD11B1 (0.69) | HSD11B1CYP3A4CYP2C19 | |
| SCHEMBL973451 | 0.88 | HSD11B1 (0.71) | HSD11B1 | |
| SCHEMBL16208168 | 0.85 | HSD11B1 (0.69) | HSD11B1 | |
| SCHEMBL16208144 | 0.85 | HSD11B1 (0.78) | HSD11B1 | |
| SCHEMBL16208170 | 0.84 | HSD11B1 (0.76) | HSD11B1CYP3A4CYP2C19 | |
| SCHEMBL16208219 | 0.84 | HSD11B1 (0.78) | HSD11B1CYP3A4CYP2C19 | |
| SCHEMBL16208053 | 0.82 | HSD11B1 (0.64) | HSD11B1CYP3A4CYP2C19 | |
| SCHEMBL16208139 | 0.81 | HSD11B1 (0.62) | HSD11B1CYP3A4CYP2C19 | |
| SCHEMBL16208068 | 0.81 | HSD11B1 (0.71) | HSD11B1CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238126-B1 | DERIVATIVES OF TETRAHYDROQUINOXALINE UREA, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF | SANOFI SA (FR) | 2014-11-05 | — | — | EP | claimed |