Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16207926 | 0.92 | HSD11B1 (0.57) | HSD11B1 | |
| SCHEMBL16208174 | 0.92 | HSD11B1 (0.77) | HSD11B1 | |
| SCHEMBL16208148 | 0.89 | HSD11B1 (0.64) | HSD11B1 | |
| SCHEMBL973876 | 0.88 | HSD11B1 (0.84) | HSD11B1 | |
| SCHEMBL16208012 | 0.82 | HSD11B1 (0.78) | HSD11B1 | |
| SCHEMBL16207937 | 0.81 | HSD11B1 (0.62) | HSD11B1 | |
| SCHEMBL16208144 | 0.80 | HSD11B1 (0.78) | HSD11B1 | |
| SCHEMBL975559 | 0.80 | HSD11B1 (0.73) | HSD11B1 | |
| SCHEMBL16208017 | 0.79 | HSD11B1 (0.47) | HSD11B1 | |
| SCHEMBL16208175 | 0.79 | HSD11B1 (0.48) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238126-B1 | DERIVATIVES OF TETRAHYDROQUINOXALINE UREA, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF | SANOFI SA (FR) | 2014-11-05 | — | — | EP | claimed |