Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16208091 | 0.90 | HSD11B1 (0.58) | HSD11B1 | |
| SCHEMBL16208022 | 0.89 | HSD11B1 (0.57) | HSD11B1 | |
| SCHEMBL16208161 | 0.89 | HSD11B1 (0.63) | HSD11B1 | |
| SCHEMBL16208194 | 0.89 | HSD11B1 (0.56) | HSD11B1 | |
| SCHEMBL16208229 | 0.89 | HSD11B1 (0.56) | HSD11B1 | |
| SCHEMBL16208198 | 0.88 | HSD11B1 (0.55) | HSD11B1 | |
| SCHEMBL16208197 | 0.88 | HSD11B1 (0.52) | HSD11B1 | |
| SCHEMBL16208170 | 0.87 | HSD11B1 (0.76) | HSD11B1 | |
| SCHEMBL16208018 | 0.87 | HSD11B1 (0.61) | HSD11B1 | |
| SCHEMBL16208204 | 0.86 | HSD11B1 (0.65) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238126-B1 | DERIVATIVES OF TETRAHYDROQUINOXALINE UREA, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF | SANOFI SA (FR) | 2014-11-05 | — | — | EP | claimed |