Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 20/20 | 0.78 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973931 | 0.90 | HSD11B1 (0.81) | HSD11B1HSD11B2CYP3A4 | |
| SCHEMBL973930 | 0.90 | HSD11B1 (0.81) | HSD11B1HSD11B2CYP3A4 | |
| SCHEMBL974109 | 0.88 | HSD11B1 (1.00) | HSD11B1HSD11B2CYP3A4 | |
| SCHEMBL975298 | 0.86 | HSD11B1 (0.84) | HSD11B1HSD11B2CYP3A4 | |
| SCHEMBL9607922 | 0.86 | HSD11B1 (0.75) | HSD11B1HSD11B2 | |
| SCHEMBL973800 | 0.85 | HSD11B1 (0.82) | HSD11B1HSD11B2CYP3A4 | |
| SCHEMBL973452 | 0.85 | HSD11B1 (0.82) | HSD11B1HSD11B2CYP3A4 | |
| SCHEMBL974188 | 0.85 | HSD11B1 (1.00) | HSD11B1HSD11B2 | |
| SCHEMBL974300 | 0.85 | HSD11B1 (1.00) | HSD11B1HSD11B2 | |
| SCHEMBL973403 | 0.84 | HSD11B1 (0.87) | HSD11B1HSD11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238126-B1 | DERIVATIVES OF TETRAHYDROQUINOXALINE UREA, PREPARATION THEREOF AND THERAPEUTIC APPLICATION THEREOF | SANOFI SA (FR) | 2014-11-05 | — | — | EP | claimed |