Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13627774 | 0.78 | FAAH (0.43) | FAAHHRH3 | |
| SCHEMBL1507061 | 0.76 | HRH3 (0.48) | FAAHHRH3 | |
| SCHEMBL1507231 | 0.76 | HRH3 (0.51) | HRH3 | |
| SCHEMBL1507240 | 0.76 | FAAH (0.47) | FAAHHRH3 | |
| SCHEMBL1507157 | 0.75 | HRH3 (0.46) | HRH3 | |
| SCHEMBL1506962 | 0.75 | HRH3 (0.51) | HRH3KDM4E | |
| SCHEMBL1507050 | 0.74 | HRH3 (0.51) | FAAHHRH3 | |
| SCHEMBL1506988 | 0.74 | HRH3 (0.47) | HRH3 | |
| SCHEMBL1507115 | 0.74 | HRH3 (0.47) | HRH3 | |
| SCHEMBL1507021 | 0.74 | HRH3 (0.47) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2300422-B1 | AZETIDINES AS HISTAMINE H3 RECEPTOR ANTAGONISTS | EVOTEC AG (DE) | 2014-11-05 | — | — | EP | claimed |