Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.45 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5279500 | 0.86 | PTGS1 (0.55) | EDNRAMAPK9ALDH1A1MAPK1KMT2A | |
| SCHEMBL7433780 | 0.86 | PTGS1 (0.55) | EDNRAMAPK9ALDH1A1MAPK1KMT2A | |
| SCHEMBL16208746 | 0.86 | PTGS1 (0.55) | EDNRAMAPK9ALDH1A1MAPK1KMT2A | |
| Acetic Acid SCHEMBL10875129 | 0.82 | PTGS1 (0.51) | EDNRAMAPK9ALDH1A1MAPK1KMT2A | |
| Acetic Acid SCHEMBL10942103 | 0.82 | PTGS1 (0.51) | EDNRAMAPK9ALDH1A1MAPK1KMT2A | |
| SCHEMBL10874124 | 0.81 | EDNRA (0.51) | EDNRAALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL18076242 | 0.81 | EDNRA (0.51) | EDNRAALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL10875005 | 0.81 | EDNRA (0.51) | EDNRAALDH1A1KMT2AMEN1HPGD | |
| Hydrochloric Acid SCHEMBL10874331 | 0.80 | EDNRA (0.50) | EDNRAKMT2AMEN1HPGD | |
| SCHEMBL7898797 | 0.80 | CYP3A4 (0.54) | MAPK9ALDH1A1MAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014174425-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF ORTHOSTASIS AND NEUROLOGICAL DISEASES | KANDULA MAHESH (IN) | 2014-10-30 | — | — | WO | disclosed |