SCHEMBL1620912

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2898132	0.91	FGFR1 (0.51)	FGFR1FLT1HTR3AHRH3LCK
	SCHEMBL1621737	0.81	HRH3 (0.51)	FGFR1FLT1HTR3AHRH3LCK
	SCHEMBL1622372	0.80	FGFR1 (0.69)	FGFR1FLT1HTR3AHRH3KCNH2
	SCHEMBL1620865	0.79	HRH3 (0.51)	FGFR1FLT1HTR3AHRH3LCK
	SCHEMBL13869844	0.76	HRH3 (0.39)	FGFR1FLT1HTR3AHRH3LCK
	SCHEMBL1797290	0.73	HRH3 (0.60)	HRH3ATML3MBTL1HRH1KCNH2
	SCHEMBL1621980	0.73	ITK (0.52)	FGFR1FLT1HTR3AHRH3LCK
	SCHEMBL1792471	0.72	HRH3 (0.58)	HRH3ATML3MBTL1XDHHRH1
	SCHEMBL13869880	0.72	FGFR1 (0.61)	FGFR1FLT1
	SCHEMBL1621132	0.71	LCK (0.50)	FGFR1FLT1HTR3AHRH3LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.