⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1458706 | 1.00 | — | — | |
| SCHEMBL1458711 | 1.00 | — | — | |
| Formic Acid SCHEMBL31336082 | 0.92 | — | — | |
| Fumaric Acid SCHEMBL1756130 | 0.88 | TSHR (0.41) | — | |
| Maleic Acid SCHEMBL1756123 | 0.88 | TSHR (0.41) | — | |
| Malic Acid SCHEMBL22367533 | 0.77 | SMN1; SMN2 (0.52) | — | |
| Citric Acid SCHEMBL22367547 | 0.77 | ALDH1A1 (0.52) | — | |
| SCHEMBL15711047 | 0.74 | GRIK1 (0.31) | — | |
| SCHEMBL22344706 | 0.74 | — | — | |
| SCHEMBL9319818 | 0.74 | GRIK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160175308-A1 | THERAPEUTIC AGENTS FOR MODULATING THYMIC FUNCTION AND/OR GROWTH AND/OR TREATING VARIOUS DISORDERS | UCL BUSINESS PLC (GB) | 2016-06-23 | — | — | US | claimed |
| EP-2991674-A1 | THERAPEUTIC AGENTS FOR MODULATING THYMIC FUNCTION AND/OR GROWTH AND/OR TREATING VARIOUS DISORDERS | UCL Business Plc. (GB) | 2016-03-09 | — | — | EP | claimed |
| WO-2014177890-A1 | THERAPEUTIC AGENTS FOR MODULATING THYMIC FUNCTION AND/OR GROWTH AND/OR TREATING VARIOUS DISORDERS | UCL BUSINESS PLC (GB) | 2014-11-06 | — | — | WO | claimed |
| US-20160175308-A1 | THERAPEUTIC AGENTS FOR MODULATING THYMIC FUNCTION AND/OR GROWTH AND/OR TREATING VARIOUS DISORDERS | UCL BUSINESS PLC (GB) | 2016-06-23 | — | — | US | disclosed |
| EP-2991674-A1 | THERAPEUTIC AGENTS FOR MODULATING THYMIC FUNCTION AND/OR GROWTH AND/OR TREATING VARIOUS DISORDERS | UCL Business Plc. (GB) | 2016-03-09 | — | — | EP | disclosed |
| WO-2014177890-A1 | THERAPEUTIC AGENTS FOR MODULATING THYMIC FUNCTION AND/OR GROWTH AND/OR TREATING VARIOUS DISORDERS | UCL BUSINESS PLC (GB) | 2014-11-06 | — | — | WO | disclosed |