SCHEMBL16212282

SCHEMBL16212282

Nc1nc(=O)n(C2CC(O)C(CO)O2)cc1F

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 6/20 0.63
ADRB1 P08588 1/20 0.63
ALB P02768 1/20 0.61
LMNA P02545 3/20 0.60
SMN1; SMN2 Q16637 3/20 0.60
DNMT3B Q9UBC3 2/20 0.54
PNP P00491 1/20 0.49
TP53 P04637 1/20 0.49
HTT P42858 1/20 0.49
PDE4D Q08499 1/20 0.49
PDE3A Q14432 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
ALOX12 P18054 1/20 0.48
ADRA1A P35348 1/20 0.48
TK1 P04183 1/20 0.48
FPR2 P25090 1/20 0.48
POLG P54098 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5982928 1.00 DNMT1 (0.63) DNMT1ADRB1ALBLMNASMN1; SMN2
SCHEMBL207023 1.00 DNMT1 (0.63) DNMT1ADRB1ALBLMNASMN1; SMN2
SCHEMBL13262186 1.00 DNMT1 (0.63) DNMT1ADRB1ALBLMNASMN1; SMN2
SCHEMBL8345 1.00 DNMT1 (0.63) DNMT1ADRB1ALBLMNASMN1; SMN2
SCHEMBL5717505 1.00 DNMT1 (0.63) DNMT1ADRB1ALBLMNASMN1; SMN2
SCHEMBL24141674 1.00 DNMT1 (0.63) DNMT1ADRB1ALBLMNASMN1; SMN2
SCHEMBL7736439 1.00 DNMT1 (0.63) DNMT1ADRB1ALBLMNASMN1; SMN2
SCHEMBL12041986 1.00 DNMT1 (0.63) DNMT1ADRB1ALBLMNASMN1; SMN2
SCHEMBL5982921 1.00 DNMT1 (0.63) DNMT1ADRB1ALBLMNASMN1; SMN2
Phosphoric Acid SCHEMBL8409010 0.95 DNMT1 (0.58) DNMT1ADRB1ALBLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116539741-A Method for detecting 5-fluorodeoxycytidine modified abundance in DNA (deoxyribonucleic acid) through LC-MS (liquid chromatography-mass spectrometry) 中国农业科学院生物技术研究所 2023-08-04 CN disclosed
CN-108699546-B Transposable element mobilization for enhancing genetic and epigenetic variability in a population 巴塞尔大学 2022-06-07 CN disclosed
US-10184142-B2 Biocatalytic production of nucleoside analogues as active pharmaceutical ingredients PLASMIA BIOTECH, S.L. (ES) 2019-01-22 US disclosed
US-20180352764-A1 MOBILISATION OF TRANSPOSABLE ELEMENTS TO ENHANCE GENETIC AND EPIGENETIC VARIABILITY IN A POPULATION UNIVERSITAT BASEL (CH) 2018-12-13 US disclosed
CN-108699546-A Transposable element mobilization for enhancing genetic and epigenetic variability in a population 巴塞尔大学 2018-10-23 CN disclosed
US-20160076070-A1 BIOCATALYTIC PRODUCTION OF NUCLEOSIDE ANALOGUES AS ACTIVE PHARMACEUTICAL INGREDIENTS PLASMIA BIOTECH, S.L. (ES) 2016-03-17 US disclosed
EP-2992107-A2 BIOCATALYTIC PRODUCTION OF NUCLEOSIDE ANALOGUES AS ACTIVE PHARMACEUTICAL INGREDIENTS Plasmia Biotech, S.L. (ES) 2016-03-09 EP disclosed
WO-2014177585-A2 BIOCATALYTIC PRODUCTION OF NUCLEOSIDE ANALOGUES AS ACTIVE PHARMACEUTICAL INGREDIENTS PLASMIA BIOTECH, S.L (ES) 2014-11-06 WO disclosed