Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 20/20 | 0.68 |
| ▸ | EED | O75530 | 18/20 | 0.68 |
| ▸ | RBBP4 | Q09028 | 18/20 | 0.68 |
| ▸ | SUZ12 | Q15022 | 18/20 | 0.68 |
| ▸ | AEBP2 | Q6ZN18 | 18/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL16213273 | 0.84 | EZH2 (0.75) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL17099648 | 0.84 | EED (0.71) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL17099641 | 0.81 | EED (0.75) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL16212991 | 0.81 | EZH2 (1.00) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL16212990 | 0.76 | EED (1.00) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL16212987 | 0.76 | EED (1.00) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL16212989 | 0.76 | EED (1.00) | EZH2EEDRBBP4SUZ12AEBP2 | |
| Formic Acid SCHEMBL16212827 | 0.74 | EED (0.96) | EZH2EEDRBBP4SUZ12AEBP2 | |
| Formic Acid SCHEMBL16212829 | 0.74 | EED (0.96) | EZH2EEDRBBP4SUZ12AEBP2 | |
| SCHEMBL16212871 | 0.73 | EZH2 (1.00) | EZH2EEDRBBP4SUZ12AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2991980-A1 | ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2016-03-09 | — | — | EP | disclosed |
| WO-2014177982-A1 | ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2014-11-06 | — | — | WO | disclosed |