Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EED | O75530 | 20/20 | 0.75 |
| ▸ | RBBP4 | Q09028 | 20/20 | 0.75 |
| ▸ | SUZ12 | Q15022 | 20/20 | 0.75 |
| ▸ | EZH2 | Q15910 | 20/20 | 0.75 |
| ▸ | AEBP2 | Q6ZN18 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17099648 | 0.96 | EED (0.71) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL16212664 | 0.87 | EZH2 (0.70) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL16212464 | 0.86 | EZH2 (0.68) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL17713628 | 0.86 | EZH2 (0.68) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL16212636 | 0.86 | EZH2 (0.68) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL16212989 | 0.86 | EED (1.00) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL16212987 | 0.86 | EED (1.00) | EEDRBBP4SUZ12EZH2AEBP2 | |
| SCHEMBL16212990 | 0.86 | EED (1.00) | EEDRBBP4SUZ12EZH2AEBP2 | |
| Formic Acid SCHEMBL16212829 | 0.84 | EED (0.96) | EEDRBBP4SUZ12EZH2AEBP2 | |
| Formic Acid SCHEMBL16212827 | 0.84 | EED (0.96) | EEDRBBP4SUZ12EZH2AEBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119390-A2 | METHODS OF TREATING CANCER | Glaxosmithkline Intellectual Property (No. 2) Limited (GB) | 2017-01-25 | — | — | EP | disclosed |
| WO-2015143424-A2 | METHODS OF TREATING CANCER | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO. 2) LIMITED (GB) | 2015-09-24 | — | — | WO | disclosed |