Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 16/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14240838 | 0.87 | MEN1 (0.42) | CHRM3CTSSCTSKMEN1KMT2A | |
| SCHEMBL14241242 | 0.83 | CHRM3 (0.51) | CHRM3 | |
| SCHEMBL14166093 | 0.82 | LMNA (0.47) | CHRM3CTSSCTSKMEN1KMT2A | |
| SCHEMBL14166268 | 0.82 | MEN1 (0.38) | CHRM3MEN1KMT2ATAAR1GABRB1 | |
| SCHEMBL14706796 | 0.81 | CHRM3 (0.45) | CHRM3CTSSCTSK | |
| SCHEMBL15768296 | 0.81 | CHRM3 (0.54) | CHRM3 | |
| SCHEMBL17074741 | 0.81 | MEN1 (0.48) | CHRM3CTSSCTSKMEN1KMT2A | |
| SCHEMBL14166340 | 0.81 | MEN1 (0.53) | CHRM3CTSSCTSKMEN1KMT2A | |
| SCHEMBL14166631 | 0.79 | CHRM3 (0.51) | CHRM3 | |
| SCHEMBL18098070 | 0.78 | CHRM3 (0.51) | CHRM3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877774-B2 | Compounds having muscarinic receptor antagonist and beta2 Adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-11-04 | — | — | US | disclosed |