Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | C1S | P09871 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | MMP12 | P39900 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14166206 | 0.99 | TDP1 (0.51) | TDP1PRSS1F2PLGPRSS2 | |
| SCHEMBL14241226 | 0.82 | TDP1 (0.50) | TDP1PRSS1F2PLGPRSS2 | |
| SCHEMBL14166234 | 0.76 | KMT2A (0.49) | TDP1KMT2AALDH1A1MEN1TAAR1 | |
| SCHEMBL416566 | 0.75 | TDP1 (0.91) | TDP1F2KMT2ASMN1; SMN2LMNA | |
| SCHEMBL14165991 | 0.75 | SMN1; SMN2 (0.43) | PRSS1F2PLGPRSS2C1S | |
| SCHEMBL15783778 | 0.74 | KMT2A (0.57) | KMT2ASMN1; SMN2ALDH1A1MEN1NPC1 | |
| SCHEMBL14241093 | 0.74 | KMT2A (0.57) | KMT2ASMN1; SMN2ALDH1A1MEN1NPC1 | |
| Hydrochloric Acid SCHEMBL14166082 | 0.73 | KMT2A (0.56) | KMT2ASMN1; SMN2ALDH1A1MEN1NPC1 | |
| Hydrochloric Acid SCHEMBL15768636 | 0.73 | KMT2A (0.56) | KMT2ASMN1; SMN2ALDH1A1MEN1NPC1 | |
| SCHEMBL15386011 | 0.73 | TDP1 (0.58) | TDP1KMT2ASMN1; SMN2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877774-B2 | Compounds having muscarinic receptor antagonist and beta2 Adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-11-04 | — | — | US | disclosed |