Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 20/20 | 0.89 |
| ▸ | ADRB2 | P07550 | 19/20 | 0.89 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15772986 | 1.00 | CHRM3 (0.89) | CHRM3ADRB2CACNA1C | |
| SCHEMBL20357905 | 1.00 | CHRM3 (0.89) | CHRM3ADRB2CACNA1C | |
| SCHEMBL15772991 | 1.00 | CHRM3 (0.89) | CHRM3ADRB2CACNA1C | |
| SCHEMBL15772988 | 1.00 | CHRM3 (0.89) | CHRM3ADRB2CACNA1C | |
| SCHEMBL15772121 | 0.96 | ADRB2 (0.88) | CHRM3ADRB2 | |
| SCHEMBL15772124 | 0.96 | ADRB2 (0.88) | CHRM3ADRB2 | |
| SCHEMBL15772126 | 0.96 | ADRB2 (0.88) | CHRM3ADRB2 | |
| SCHEMBL14695770 | 0.96 | CHRM3 (0.85) | CHRM3ADRB2CACNA1C | |
| SCHEMBL14695772 | 0.96 | CHRM3 (0.85) | CHRM3ADRB2CACNA1C | |
| SCHEMBL14166220 | 0.96 | CHRM3 (0.85) | CHRM3ADRB2CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877774-B2 | Compounds having muscarinic receptor antagonist and beta2 Adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-11-04 | — | — | US | disclosed |