Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.57 |
| ▸ | RXRB | P28702 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | RXRG | P48443 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 5/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.52 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16213801 | 0.90 | KMT2A (0.55) | SMN1; SMN2NR4A2KMT2AMAOBNPC1 | |
| SCHEMBL14240817 | 0.88 | RXRA (0.57) | RXRARXRBSMN1; SMN2RXRGTSHR | |
| SCHEMBL14166035 | 0.85 | RXRA (0.54) | RXRARXRBSMN1; SMN2RXRGTSHR | |
| SCHEMBL19984677 | 0.81 | RXRA (0.57) | RXRARXRBSMN1; SMN2RXRGTSHR | |
| Hydrochloric Acid SCHEMBL15768201 | 0.80 | SMN1; SMN2 (0.60) | RXRARXRBSMN1; SMN2RXRGTSHR | |
| SCHEMBL19984429 | 0.78 | CHRM3 (0.62) | RXRARXRBSMN1; SMN2RXRGTSHR | |
| SCHEMBL20373866 | 0.78 | CHRM3 (0.62) | RXRARXRBSMN1; SMN2RXRGTSHR | |
| SCHEMBL14240961 | 0.78 | KMT2A (0.55) | SMN1; SMN2NR4A2KMT2AMAOBNPC1 | |
| SCHEMBL20373372 | 0.77 | CHRM3 (0.61) | RXRARXRBSMN1; SMN2RXRGTSHR | |
| SCHEMBL1750167 | 0.77 | NR4A2 (0.86) | RXRARXRBSMN1; SMN2RXRGTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877774-B2 | Compounds having muscarinic receptor antagonist and beta2 Adrenergic receptor agonist activity | CHIESI FARMACEUTICI S.P.A. (IT) | 2014-11-04 | — | — | US | disclosed |