SCHEMBL16213864

SCHEMBL16213864

CCc1nc(NCCS(=O)(=O)O)nc(Nc2ccc(S(=O)(=O)O)cc2)n1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 14/20 0.53
CA2 P00918 14/20 0.53
CA9 Q16790 14/20 0.53
CA12 O43570 10/20 0.47
CA14 Q9ULX7 8/20 0.47
CA5A P35218 3/20 0.46
CA4 P22748 2/20 0.46
CA6 P23280 2/20 0.46
CA7 P43166 2/20 0.46
CA5B Q9Y2D0 1/20 0.46
CA3 P07451 1/20 0.46
KCNH3 Q9ULD8 2/20 0.42
NR1I2 O75469 1/20 0.40
AHR P35869 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
CA13 Q8N1Q1 1/20 0.40
PDE4B Q07343 1/20 0.40
PDE4D Q08499 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15984417 0.90 CA1 (0.66) CA1CA2CA9CA12CA14
SCHEMBL17033145 0.89 CA9 (0.49) CA1CA2CA9CA12CA14
SCHEMBL10273544 0.88 CA9 (0.52) CA1CA2CA9CA12CA14
SCHEMBL10169008 0.88 CA1 (0.52) CA1CA2CA9CA12CA14
SCHEMBL14817402 0.88 CA1 (0.52) CA1CA2CA9CA12CA14
SCHEMBL16213845 0.86 KCNH3 (0.41) CA1CA2CA9KCNH3PDE4B
SCHEMBL13475969 0.85 CA1 (0.50) CA1CA2CA9CA12CA14
SCHEMBL13012829 0.85 CA9 (0.57) CA1CA2CA9CA12CA14
SCHEMBL14817386 0.85 CA9 (0.52) CA1CA2CA9CA12CA14
SCHEMBL10169010 0.84 CA1 (0.49) CA1CA2CA9CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8876915-B2 Coloring composition and ink for inkjet recording FUJIFILM CORPORATION (JP) 2014-11-04 US disclosed