Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841812 | 0.87 | CAPN1 (0.44) | CAPN1 | |
| SCHEMBL3841704 | 0.87 | CAPN1 (0.44) | CAPN1 | |
| SCHEMBL3840752 | 0.87 | CAPN1 (0.44) | CAPN1 | |
| SCHEMBL3842586 | 0.87 | CAPN1 (0.44) | CAPN1 | |
| SCHEMBL12990568 | 0.86 | HPGD (0.35) | CAPN1HPGDHTTSMN1; SMN2 | |
| SCHEMBL3840104 | 0.83 | CAPN1 (0.41) | CAPN1 | |
| SCHEMBL12126782 | 0.82 | MC4R (0.33) | SMN1; SMN2CYP3A4OPRD1 | |
| SCHEMBL28695039 | 0.81 | HPGD (0.36) | CAPN1HPGDHTTSMN1; SMN2 | |
| SCHEMBL22688030 | 0.81 | HPGD (0.36) | CAPN1HPGDHTTSMN1; SMN2 | |
| SCHEMBL12643782 | 0.78 | CYP3A4 (0.31) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8877928-B2 | Pegylated cyclopamine analogue, preparation method and uses thereof | SHANDONG UNIVERSITY (CN) | 2014-11-04 | — | — | US | disclosed |