Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 9/20 | 0.31 |
| ▸ | CTSK | P43235 | 6/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 2/20 | 0.30 |
| ▸ | CTSB | P07858 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22688030 | 1.00 | HPGD (0.36) | HPGDHTTSMN1; SMN2CAPN1BCHE | |
| SCHEMBL18226807 | 0.83 | CTSS (0.40) | HTTSMN1; SMN2CAPN1NFKB1NFKB2 | |
| SCHEMBL18226806 | 0.83 | CTSS (0.40) | HTTSMN1; SMN2CAPN1NFKB1NFKB2 | |
| SCHEMBL3654901 | 0.82 | CAPN1 (0.39) | HPGDHTTSMN1; SMN2CAPN1BCHE | |
| SCHEMBL16214295 | 0.81 | CAPN1 (0.38) | HPGDHTTSMN1; SMN2CAPN1 | |
| SCHEMBL28694914 | 0.80 | CAPN1 (0.42) | CAPN1CTSSCTSKACECTSL | |
| SCHEMBL22688083 | 0.80 | CAPN1 (0.42) | CAPN1CTSSCTSKACECTSL | |
| SCHEMBL3735243 | 0.79 | CAPN1 (0.40) | HPGDHTTSMN1; SMN2CAPN1BCHE | |
| SCHEMBL28697358 | 0.77 | HPGD (0.36) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL28697357 | 0.77 | HPGD (0.36) | HPGDHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114173824-A | Antibody drug conjugates | 武田药品工业株式会社 | 2022-03-11 | — | — | CN | disclosed |