Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16214692 | 0.98 | ACACB (0.69) | ACACB | |
| SCHEMBL16214694 | 0.95 | ACACB (0.64) | ACACB | |
| SCHEMBL16235542 | 0.82 | ACACB (1.00) | ACACB | |
| SCHEMBL16235540 | 0.82 | ACACB (1.00) | ACACB | |
| SCHEMBL11969450 | 0.81 | ACACB (0.58) | ACACB | |
| SCHEMBL16214700 | 0.81 | ACACB (0.64) | ACACB | |
| SCHEMBL16255176 | 0.79 | ACACB (1.00) | ACACB | |
| SCHEMBL16214693 | 0.79 | ACACB (0.65) | ACACB | |
| SCHEMBL16240171 | 0.79 | ACACB (0.57) | ACACB | |
| SCHEMBL16240173 | 0.79 | ACACB (0.57) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614054-B1 | ETHYNE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2014-11-19 | — | — | EP | disclosed |
| US-8877754-B2 | Compounds, pharmaceutical compositions and uses thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-11-04 | — | — | US | disclosed |