SCHEMBL16215310

SCHEMBL16215310

CCCCCCCCCC(Oc1ccc(-c2ccc(C#N)cc2)cc1)[Si](C)(C)O[Si](C)(C)C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ALDH1A1 P00352 3/20 0.44
HPGD P15428 3/20 0.44
KDM4E B2RXH2 3/20 0.44
HTT P42858 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
MGLL Q99685 2/20 0.39
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
GRM2 Q14416 1/20 0.36
PTGES O14684 3/20 0.36
ALOX5 P09917 3/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
HRH2 P25021 2/20 0.34
HRH1 P35367 2/20 0.34
HRH3 Q9Y5N1 2/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17225179 0.94 TSHR (0.43) TSHRHSD17B10ALDH1A1HPGDKDM4E
SCHEMBL16215366 0.85 TSHR (0.48) TSHRHSD17B10ALDH1A1HPGDKDM4E
SCHEMBL6253773 0.80 TSHR (0.52) TSHRHSD17B10ALDH1A1HPGDKDM4E
SCHEMBL17225199 0.79 CYP11B1 (0.41)
SCHEMBL9448649 0.78 NR5A1 (0.44) TSHRHSD17B10ALDH1A1KDM4EGRM2
SCHEMBL28703168 0.78 TSHR (0.50) TSHRHSD17B10ALDH1A1HPGDKDM4E
SCHEMBL6250338 0.77 TSHR (0.52) TSHRHSD17B10ALDH1A1HPGDKDM4E
SCHEMBL29116633 0.77 TSHR (0.52) TSHRHSD17B10ALDH1A1HPGDKDM4E
SCHEMBL29116693 0.77 TSHR (0.52) TSHRHSD17B10ALDH1A1HPGDKDM4E
SCHEMBL9450590 0.77 TSHR (0.52) TSHRHSD17B10ALDH1A1HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9175220-B2 High scattering smectic liquid crystal material and display device using the same HALATION PHOTONICS CORPORATION (CN) 2015-11-03 US disclosed
EP-2799516-A1 LIQUID CRYSTAL MATERIAL OF SMECTIC PHASE IN HIGH SCATTERING STATE AND DISPLAY DEVICE THEREOF Halation Photonics Corporation (CN) 2014-11-05 EP disclosed