Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 3/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 4/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9154542 | 0.85 | NR5A1 (0.49) | NR5A1LTA4HALDH2ESR1ADRA2A | |
| SCHEMBL16215310 | 0.78 | TSHR (0.46) | KDM4EALDH1A1HSD17B10TSHRGRM2 | |
| SCHEMBL9584542 | 0.73 | NR5A1 (0.53) | NR5A1LTA4HESR1ADRA2AADORA3 | |
| SCHEMBL7769925 | 0.73 | NR5A1 (0.53) | NR5A1LTA4HESR1ADRA2AADORA3 | |
| SCHEMBL9628392 | 0.73 | NR5A1 (0.58) | NR5A1LTA4HESR1ADRA2AADORA3 | |
| SCHEMBL9630337 | 0.73 | NR5A1 (0.58) | NR5A1LTA4HESR1ADRA2AADORA3 | |
| SCHEMBL7777459 | 0.73 | NR5A1 (0.58) | NR5A1LTA4HALDH2ESR1ADRA2A | |
| SCHEMBL7785543 | 0.73 | NR5A1 (0.58) | NR5A1LTA4HALDH2ESR1ADRA2A | |
| SCHEMBL7785538 | 0.73 | NR5A1 (0.58) | NR5A1LTA4HALDH2ESR1ADRA2A | |
| SCHEMBL7784172 | 0.73 | NR5A1 (0.58) | NR5A1LTA4HALDH2ESR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5210247-A | ORGANOSILYLALKYLAROMATIC COMPOUNDS | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 1993-05-11 | — | — | US | disclosed |